Medetomidine is a non-opioid veterinary anesthetic drug and a synthetic alpha-2-adrenoceptor agonist that is not approved for human use. Increasingly, it’s being used with illicitly manufactured fentanyl, xylazine (another, similar, non-opioid, animal sedative), heroin, and other street drugs in several parts of the U.S.1 Because it’s an emerging adulterant, the Centers for Disease Control is closely monitoring it.
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