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Patients who have urine drug test (UDT) samples suggestive of buprenorphine “ADD-IN” (commonly referred to as “spiking”). Buprenorphine is used to treat pain and opioid use disorder (OUD).

Spiking a urine sample represents intentional addition of buprenorphine tablet or residue directly into the urine to mimic adherence with prescribed buprenorphine.

Spiking suggests that treatment is not working – especially in patients continuing illicit drug use. Detecting spiking allows clinicians to adjust or intensify the treatment plan.”


National Association of Drug Diversion Investigators Federal Tax ID: 52-1660752 / DUNS Number: 073539913

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