Bupropion, sold under the brand names Wellbutrin and Zyban among others, is an atypical antidepressant primarily used to treat major depressive disorder and to support smoking cessation.
An antidepressant with broad off-label use, including ADHD and smoking cessation. A derivative of cathinone, which is an amphetamine analog. The drug targets the brain reward circuits, similarly to cocaine, methamphetamine, and nicotine.
In the setting of abuse, high-dose bupropion is ground up for snorting and creates a euphoric high similar to cocaine.