N,N-Dimethylpentylone

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Synonyms
Dipentylone

N,N-Dimethylpentylone is classified as a novel stimulant and substituted cathinone.

Substituted cathinones are modified based on the structure of cathinone, an alkaloid found in the Khat plant. Novel stimulants have been reported to cause psychoactive effects similar to amphetamines. Novel stimulants have also caused adverse events, including deaths.

Structurally similar compounds include N-ethyl pentylone, pentylone, and eutylone. N-Ethyl pentylone and pentylone are Schedule I substances in the United States, while eutylone can be considered an isomer of pentylone. N,N-Dimethylpentylone is not explicitly
scheduled in the United States; however, this drug may be considered a scheduled substance being an isomer of N-ethyl pentylone.

NPS Discovery Tox Report – Dec 2021

April 22, 2022 NDEWS Alert: NPS Discovery issued a public alert this week with recommendations for public health, laboratories, clinicians, and medical examiners and coroners. While the substituted cathinone eutylone was the most commonly encountered synthetic stimulant in forensic casework in 2020 and 2021, increases in N,N-dimethylpentylone are now being seen in toxicology testing. To date, NPS Discovery has identified N,N-dimethylpentylone in at least 32 forensic cases originating from various states and regions across the US.

March 24, 2023 NDEWS Alert: Online mentions of N,N-Dimethylpentylone

Context: NDEWS Sentinel Sites in Florida and Atlanta, GA have recently reported significant increases in findings for the drug N,N-Dimethylpentylone, a cathinone derivative with stimulant effects.

What was found? N,N-Dimethylpentylone first emerged in drug-related subreddit discussions in mid-2022 and has since seen an uptick in activity.

How is N,N-Dimethylpentylone being discussed? Online discussion of N,N-Dimethylpentylone appears to be largely negative. Most discussions are concerned with the increasingly common substitution of MDMA with dipentylone. Many commenters are urging others to test their MDMA. Discussion from commenters who are taking the drug intentionally is mixed, with some endorsing the use of the drug and others warning of its dangerous effects.

December 2022 NFLIS Snapshot Report – found specimens in the US.

National Association of Drug Diversion Investigators Federal Tax ID: 52-1660752 / DUNS Number: 073539913

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