N,N-Dimethylpentylone is classified as a novel stimulant and substituted cathinone.
Substituted cathinones are modified based on the structure of cathinone, an alkaloid found in the Khat plant. Novel stimulants have been reported to cause psychoactive effects similar to amphetamines. Novel stimulants have also caused adverse events, including deaths.
Structurally similar compounds include N-ethyl pentylone, pentylone, and eutylone. N-Ethyl pentylone and pentylone are Schedule I substances in the United States, while eutylone can be considered an isomer of pentylone. N,N-Dimethylpentylone is not explicitly
scheduled in the United States; however, this drug may be considered a scheduled substance being an isomer of N-ethyl pentylone.
April 22, 2022 NDEWS Alert: NPS Discovery issued a public alert this week with recommendations for public health, laboratories, clinicians, and medical examiners and coroners. While the substituted cathinone eutylone was the most commonly encountered synthetic stimulant in forensic casework in 2020 and 2021, increases in N,N-dimethylpentylone are now being seen in toxicology testing. To date, NPS Discovery has identified N,N-dimethylpentylone in at least 32 forensic cases originating from various states and regions across the US